Current Issue : October - December Volume : 2019 Issue Number : 4 Articles : 6 Articles
Background: To present the follow-up outcomes of a modified technique of transscleral suture fixation of posterior\nchamber intraocular lens (PCIOL) in eyes with inadequate capsule support.\nMethods: A retrospective chart review of 21 patients underwent transscleral suture fixation of a foldable 3-looped\nhaptics one-piece PCIOL implantation through scleral pockets was conducted. Preoperative data and follow-up data\nfor at least 3 months were collected for all patients.........................
Background: Femtosecond laser-assisted LASIK (FS-LASIK) can make ultra-thin corneal flap accurately. MEL 90\nexcimer laser provides Triple-A ablation mode, which significantly reduces the amount of corneal tissue cutting.\nThis study aimed to investigate the visual and refractive outcomes in patients with high myopia after thin-flap FSLASIK\nusing the 500 Hz pulse rate of the Triple-A profile.\nMethods: This prospective study included 90 eyes from 90 patients received thin-flap FS-LASIK using the 500 Hz pulse\nrate of the Triple-A profile. According to the pre-operative spherical equivalence (SE), the treated eyes were divided\ninto two groups: the first group (ranged from - 9.0D to - 6.0D) and the second group (ranged from - 11.15D to - 9.0\nD). The parameters evaluated pre-operatively and 6 month post-operatively included uncorrected distance visual acuity\n(UDVA), corrected distance visual acuity (CDVA), SE, efficacy and safety index, posterior central elevation, and corneal\nhigher-order aberrations (HOAs).................
Background: Myopia is a common visual disorder with increasing prevalence. Halting progression of myopia is\ncritical, as high myopia can be complicated by a number of vision-compromising conditions.\nMethods: Literature search was conducted in the following databases: Medical Literature Analysis and Retrieval\nSystem Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), Cochrane Database of Systematic Reviews (CDSR),\nDatabase of Abstracts of Reviews of Effects (DARE) and Centre for Reviews and Dissemination (CRD) Health\nTechnology Assessment (HTA) database. Systematic reviews and meta-analyses investigating the efficacy and safety\nof multiple myopia interventions vs control conditions, were considered. Methodological quality and quality of\nevidence of eligible studies were assessed using the ROBIS tool and GRADE rating. The degree of overlapping of\nindex publications in the eligible reviews was calculated with the corrected covered area (CCA).\nResults: Forty-four unique primary studies contained in 18 eligible reviews and involving 6400 children were\nincluded in the analysis. CCA was estimated as 6.2% and thus considered moderate. Results demonstrated the\nsuperior efficacy of atropine eyedrops; 1% atropine vs placebo (change in refraction: -0.78D, [- 1.30 to - 0.25] in 1\nyear), 0.025 to 0.05% atropine vs control (change in refraction: -0.51D, [- 0.60 to - 0.41] in 1 year), 0.01% atropine vs\ncontrol (change in refraction: -0.50D, [- 0.76 to - 0.24] in 1 year). Atropine was followed by orthokeratology (axial\nelongation: - 0.19 mm, [- 0.21 to - 0.16] in 1 year) and novel multifocal soft contact lenses (change in\nrefraction: -0.15D, [- 0.27 to - 0.03] in 1 year). As regards adverse events, 1% atropine induced blurred near\nvision (odds ratio [OR] 9.47, [1.17 to 76.78]) and hypersensitivity reactions (OR 8.91, [1.04 to 76.03]).\nConclusions: Existing evidence has failed to convince doctors to uniformly embrace treatments for myopic\nprogression control, possibly due to existence of some heterogeneity, reporting of side effects and lack of\nlong-term follow-up. Research geared towards efficient interventions is still necessary....
Background: The purpose of this case series was to further characterize proteasome inhibitor associated chalazia\nand blepharitis, to investigate outcomes of different management strategies, and to propose a treatment algorithm\nfor eyelid complications in this patient population.\nMethods: This retrospective case series included sixteen patients found to have chalazia and/or blepharitis while\nreceiving proteasome inhibitors for plasma cell disorders at Mount Sinai Hospital in New York, NY from January\n2010 through January 2017. Main outcomes were complete resolution of eyelid complications and time to resolution.\nStudentâ??s t-test was used to compare average values and Fisherâ??s exact test was used to compare proportions.\nResults: Fourteen patients had chalazia and 10 had blepharitis. Chalazia averaged 5.4 mm, and 11 patients with chalazia\nexperienced two or more lesions. Median follow-up time was 17months. Average time from bortezomib exposure to\nonset of first eyelid complication was 3.4 months. Chalazia episodes were more likely to completely resolve\nthan blepharitis episodes (p = 0.03). Ocular therapy alone was trialed for an average of 1.8 months before\nproceeding to bortezomib omission. Average time to eyelid complication resolution using ocular therapy\nalone was 1.8 months versus 3.1 months after bortezomib omission. In this series, the combination of ocular\ntherapy and bortezomib omission led to complete resolution of eyelid complications more often than ocular\ntherapy alone.\nConclusion: Proteasome inhibitor associated eyelid complications were identified in sixteen patients with\nplasma cell disorders. Eyelid complications may be treated with a 2-month trial of conservative ocular therapies alone,\nfollowed by continuation of ocular therapy in combination with bortezomib omission if eyelid signs persist....
Background: To investigate, using optical coherence tomography angiography (OCT-A), changes in perfusion\ndensity and in the foveal avascular zone (FAZ) in eyes with idiopathic vitreomacular traction (VMT) after ocriplasmin\ninjection.\nMethods: In this pilot study, we enrolled sixteen VMT eyes treated with intravitreal ocriplasmin injection. Sixteen\nhealthy eyes were considered as controls. Macular perfusion density in 3 plexuses [superficial capillary plexus (SCP),\ndeep capillary plexus (DCP), choriocapillaris (CC)] was calculated at baseline and at 1 month after injection.\nResults: After injection, VMT anatomically resolved in 9 eyes (56.2%), whereas 7 eyes (43.8%) achieved an\nincomplete VMT separation.............................
Background: It is unclear whether post-operative errors after toric intraocular\nlens implantation would be more amenable to pre-operative correction\nwith a fixed adjustment or a correction ratio that scales with the magnitude of\npre-operative astigmatism. Purpose: To investigate the effect of pre-operative\nanterior corneal astigmatism orientation on outcomes of toric intraocular\nlens implantation in a large population. Methods: A retrospective cohort\nstudy of 625 patients undergoing refractive lens exchange through a superior\nclear corneal incision with Oculentis M-Plus toric intraocular lens implantation\nat an Optical Express, Inc. located in the United Kingdom and Ireland.\nPatients were stratified by axis of astigmatism on automated keratometry as\nwith-the-rule, against-the-rule, or oblique. Analysis of visual acuity and refractive\noutcomes was performed using American National Standards Institute\n(ANSI) guidelines on astigmatic corrections with non-vector as well as\nvector analyses. Analysis was limited to one eye per patient. Results: Patients\nwho had with-the-rule (WTR) astigmatism, compared with oblique and\nagainst-the-rule (ATR), had higher vector magnitudes of surgically induced\nrefractive correction (2.89D, 2.55D, 2.42D; p < 0.001), and larger correction\nratios (1.18, 1.02, 1.07; p < 0.001). This created a change of astigmatic axis in\nthe with-the-rule cohort from WTR pre-operative astigmatism to an average\nATR post-operative astigmatism. The overcorrection in the WTR cohort averaged\n0.30D. We found that the absolute dioptric overcorrection among\nWTR patients did not differ significantly with magnitude of corneal astigmatism,\nbut the correction ratio was lower among those with higher baseline\ncylindrical errors (p = 0.93 and 0.0002, respectively). Conclusions: Refractive\nlens exchange surgery using toric intraocular lenses overcorrected patients\nwho had with-the-rule astigmatism. Degree of overcorrection did not vary\nwith severity of pre-operative astigmatism. Incorporation of axis of astigmatism\nin lens selection and reduction of astigmatic correction among\nwith-the-rule patients by an absolute value of 0.25D - 0.35D, rather than\nproportional adjustments, may reduce cylindrical over-correction....
Loading....